Endocrine Abstracts

Introduction: Prolactin is a multifunctional pituitary hormone. The effect of prolactin on platelet activation is not well understood. Prolactinomas are the most common type of pituitary adenomas, and they are medically responsive to dopamine agonists. Mean platelet volume (MPV) is a marker of platelet function and activation. The aim of this study was to evaluate MPV values before and 6 months of cabergoline treatment when normoprolactinemia was achieved.<p class="abstext...

There is growing evidence that platelet indices correlate with functional status of platelets and with the risk of cardiovascular events. In this study we aimed to assess clinical correlates of mean platelet volume (MPV) in patients with abdominal obesity from different age groups. We investigated 111 adults with abdominal obesity, not receiving antiplatelet therapy. Abdominal obesity was defined in accordance with IDF criteria (2006). Group 1 included 44 patients aged 26&#150...

Aim: Of the study was to establish normal penile size and testicular volume in healthy Lithuanian newborns.Methods: Of 1204 newborn boys were examined in Panevėžys Hospital due to genitometry. Those with cryptorchidism or hypospadias were excluded. Penis size was measured in 1042 and testicular volume in 712 healthy newborns. The stretched penile length was measured between the pubic ramus and the tip of the glans and the diameter – in...

Background: Macrosomia (BW >4.5 kg) is a well-recognised complication of maternal hyperglycaemia and is associated with poor maternal and foetal outcomes. Traditional risk factors of macrosomia do not fully explain all variation as it can happen in normoglycaemia and in well-controlled diabetes. The relative contributions of these factors in different ethnicities are unknown. We investigated the predictors of BW in South Asian (SA) and White Caucasian (WC) pregnancies, and...

Poland was considered as a mild-to-moderate iodine deficiency area according to results of a nation-wide survey conducted in early 1990-ties. The obligatory iodine prophylaxis program based on iodization of house-hold salt (30 mg of iodide/1 kg of salt) was therefore introduced in 1997.The aim of the study was to assess the real impact of the Polish iodine prophylaxis model on thyroid volume in schoolchildren.Material and methods: ...

Introduction: Adequate iodine intake is important in pregnant women.Objective: To determinate iodine status and thyroid volumen (TV) in healthy pregnant women from Navarra (Spain), and to evaluate possible influence of diet.Methods: A cross-sectional study of 144 women in the first trimester of pregnancy (single pregnancies) was carried during 2014. We measured thyroid-stimulating hormone (TSH), free thyroxine (fT4) and antithyroid...

Introduction: First-line somatostatin analogue treatment may be an effective alternative option to surgery for some patients with GH-secreting pituitary macroadenoma. The PRIMARYS study aimed to investigate the impact of primary lanreotide Autogel 120 mg treatment on tumour volume and GH/IGF1 control in treatment-naïve acromegalic patients over a one-year time course.Methods: PRIMARYS was an international, multicentre, open-label, single arm, phase ...

Aim: To study character of neuroendocrine disorders in children and adolescents with the Turkish saddle volume formations.Materials and methods: we examined 35 children and adolescents, 17 girls and 18 boys among them with the Turkish saddle volume formations at the neuroendocrine department of the Center for the scientific and clinical study of endocrinology. All examinees underwent general clinical examination as well as biochemical and hormonal invest...

Background: Hypogonadism is related to additional endocrine abnormalities. Thyroid abnormalities may be common in hypogonadism patients, although this association is not clear.Objective: In this study, we examined the incidence of thyroid disorders in hypogonadisms.Methods: A case–control study of 68 hypogonadal patients and 74 age-matched healthy controls from the general population was conducted. Thyroid function, thyroid vo...

Introduction: Testosterone therapy in elderly is controversial, because of the effect on prostate. The old age itself is not a contraindication in the therapy of hypogonadism.Aim: We analyze the effect of 24 months of therapy with testosterone undecanoat depot (1000 mg/4 ml) (TUD) on the volume of the prostate (VP).Patients and method: The patients were 79 symptomatic hypogonadic men, with normal value of PSA (<4 g/l). The urol...